Hailan Hu Lab

Chen M, Ma S, Liu H, Dong Y, Tang J, Ni Z, Tan Y, Duan C, Li H, Huang H, Li Y, Cao X, Lingle JC, Yang Y, Hu H*.(2024). Brain region-specific action of ketamine as a rapid antidepressant. Science. 385,eado7010 [pdf]
Ma S#, Chen M#, Jiang Y, Xiang X, Wang S, Wu Z, Li S, Cui Y, Wang J, Zhu Y, Zhang Y, Ma H, Duan S, Li H, Yang Y, Lingle JC, Hu H*.(2023). Sustained antidepressant effect of ketamine through NMDAR trapping in the LHb. Nature. 622: 802-809 [pdf]
Dong Y, Li Y, Xiang X, Xiao Z, Hu J, Li Y, Li H, Hu H*.(2023). Stress relief as a natural resilience mechanism against depression-like behaviors. Neuron. 111: 1-13 [pdf]
Fan Z, Chang J, Liang Y, Zhu H, Zhang C, Zheng D, Wang J, Xu Y, Li Q, Hu H*.(2023). Neural mechanism underlying depressive-like state associated with social status loss. Cell. 186: 1–17 [pdf]
Zhang C#, Zhu H#*, Ni Z#, Xin Q, Zhou T, Wu R, Gao G, Gao Z, Ma H, Li H, He M, Zhang J, Chen H, Hu H*.(2022). Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition. Neuron. 110: 516-531(Cover article) [pdf]
Hu H*, Cui Y and Yang Y.(2020). Circuits and functions of the lateral habenula in health and in disease. Nature Reviews Neuroscience. 21: 277–295. (invited review) [pdf]
Cui Y, Hu S, Hu H.(2019). Lateral Habenular Burst Firing as a Target of the Rapid Antidepressant Effects of Ketamine. Trends in Neurosciences. 42(3), 179-191.(invited review, cover article) [pdf]
Cui Y, Yang Y, Dong Y and Hu H.(2018). Decoding depression: Insights from glial and ketamine regulation of neuronal burst firing in lateral habenula. Cold Spring Harbor Symp Quant Biol. Volume 83, Brain and Behavior: Order and Disorder in the Nervous System (invited review) [pdf]
Yang Y, Cui Y, Sang K, Dong Y, Ni Z, Ma S, Hu H.(2018). Ketamine blocks bursting in the lateral habenula to rapidly relieve depression. Nature. 554: 317-22.(Research article, Featured by Nature, Nat. Rev. Neuro. and Neuron) [pdf]
Cui Y, Yang Y, Ni Z, Dong Y, Sang K, Cai G, Foncelle A, Ma S, Sang K, Tang S, Li Y, Shen Y, Berry H, Wu S, Hu H.(2018). Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression. Nature. 554: 323-27.(Research article, featured by Nature, Nat. Rev. Neuro. and Neuron) [pdf]
Zhou TT, Zhu H, Fan ZX, Wang F, Chen Y, Liang HX, Yang ZF, Zhang L, Lin LN, Zhan Y, Wang Z, Hu H.(2017). History of winning remodels thalamo-PFC circuit to reinforce social dominance. Science. 357: 162-168 (Research article, featured by Nat. Rev. Neuro.) [pdf]
Hu H.(2016). Reward and aversion. Annual Review of Neuroscience. 39: 297-324. (Invited review) [pdf]
Lv Q, Yang L, Li G, Wang Z, Shen Z, Yu W, Jiang Q, Hou B, Pu J, Hu H*, Wang Z*.(2015). Large-scale persistent network reconfiguration induced by ketamine in anesthetized monkeys: relevance to mood disorders. Biological Psychiatry. 79(9): 765-775 [pdf]
Xiu JB, Zhang Q, Zhou T, Zhou TT, Hu H*.(2014). Visualizing an emotional valence map in the limbic forebrain by TAI-FISH. Nature Neuroscience. 17: 1552-1559. [pdf]
Wang F, Kessels H*, Hu H*.(2014). The mouse that roared - neural mechanisms of social hierarchy. Trends in Neuroscience. 11: 674-682.(Invited review, cover article, *co-corresponding author) [pdf]
Li K, Zhou T, Liao L, Yang Z, Wong C, Henn F, Malinow R, Yates J, Hu H*.(2013). βCaMKII in lateral habenula mediates core symptoms of depression. Science. 341:1016-1020. (Featured by Nat. Rev. Neuro. and JAMA) [pdf]
Wang F, Zhu J, Zhu H, Zhang Q, Lin Z, Hu H*.(2011). Bidirectional control of social hierarchy by synaptic efficacy in medial prefrontal cortex. Science. 334: 693-697. (Featured by Science, 334: 608-9) [pdf]

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